Xiao-jia CHEN 陳肖家

Assistant Professor

 

Academic Qualifications

• MSc, PhD, University of Macau

• BSc, MSc, Peking University

 

Teaching

TBD

 

Research

 

Research Interests                                                                                                            

 

We are looking for postgraduate students who are interested in pharmaceutical analysis and Chinese medicines quality evaluation to join our research group. For further details, please contact Dr. Chen at xiaojiachen@umac.mo

 

 

Publications

 

Journal Articles

  1. Zhang, Q.R., Yu, H., Qi, J., Tang, D.S., Chen, X.J., Wan, J.B., Li, P., Hu, H., Wang, Y.T., Hu, Y.J. Natural formulas and the nature of formulas: Exploring potential therapeutic targets based on traditional Chinese herbal formulas. Plos One. 2017, 12(2): e0171628.
  2. Xu, X.H., Li, T., Fong, C.M.V., Chen, X.P., Chen, X.J., Wang, Y.T., Huang, M.Q., Lu, J.J. Saponins from Chinese Medicines as Anticancer Agents. Molecules. 2016, 21(10): 1326.
  3. Chen, X.J., Zhang, X.J., Shui, Y.M., Wan, J.B., Gao, J.L. Anticancer activities of protopanaxadiol- and protopanaxatriol type ginsenosides and their metabolites. Evidence-Based Complementary and Alternative Medicine. 2016, 5738694.
  4. Chen, M.H., Chen, X.J. (Co-first author), Wang, M., Lin, L.G., Wang, Y.T. Ophiopogon japonicus—A phytochemical, ethnomedicinal and pharmacological review. Journal of Ethnopharmacology. 2016, 181 : 193-213.
  5. Chen, X.J., Qiu, J.F., Wang, Y.T., Wan, J.B. Discrimination of three Panax species based on difference in volatile organic compounds using static headspace GC-MS-based metabolomics approach. American Journal of Chinese Medicine. 2016, 44(3) : 663-676.
  6. Zhang, L.L., Tian, K., Tang, Z.H., Chen, X.J., Bian, Z.X., Wang, Y.T., Lu, J.J. Phytochemistry and pharmacology of Carthamus tinctorius L. American Journal of Chinese Medicine. 2016, 44(2) : 197-226.
  7. Tang, Z.H., Li, T., Tong, Y.G., Chen, X.J., Chen, X.P., Wang, Y.T., Lu, J.J. A systematic review of the anticancer properties of compounds isolated from Licorice (Gancao). Planta Medica. 2015, 81(18): 1670-1687.
  8. Chen, X.J., Tang, Z.H., Li, X.W., Xie, C.X., Lu, J.J., Wang, Y.T. Chemical constituents, quality control, and bioactivity of Epimedii Folium (Yinyanghuo). American Journal of Chinese Medicine. 2015, 43(5): 783-834.
  9. Cai, Y., Li, X.W., Li, M., Chen, X.J., Hu, H., Ni, J.Y., Wang, Y.T. Traceability and quality control in traditional Chinese medicine: From chemical fingerprint to two-dimensions. Evidence-Based Complementary and Alternative Medicine. 2015, 251304.
  10. Yang, Z.M., Zhao, J., Lao, K.M., Chen, X.J., Leong, F., Wang, C.Z., Yuan, C.S., Li, S.P. Determination of six polyynes in Oplopanax horridus and Oplopanax elatus using polyethylene glycol modified reversed migration microemulsion electrokinetic chromatography. Electrophoresis. 2014, 35(20), 2959-2964.
  11. Li, G.L, Han, W.L., Jiang, W., Zhang, D.M., Ye, W.C., Chen, X.J., Ma, A.D. Quantitative determination of arenobufagin in rat plasma by ultra fast liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2013, 939, 86-91.
  12. Xu, J., Han, Q.B., Li, S.L., Chen, X.J., Wang, X.N., Zhao, Z.Z., Chen, H.B. Chemistry, bioactivity and quality control of Dendrobium, a commonly used tonic herb in traditional Chinese medicine. Phytochemistry Reviews, 2013, 12, 341-367.
  13. Lao, K.M., Han, D.Q., Chen, X.J., Zhao, J., Wang, T.J., Li, S.P. Simultaneous determination of seven hydrophilic bioactive compounds in water extract of Polygonum multiflorum using pressurized liquid extraction and short-end injection micellar electrokinetic chromatography. Chemistry Central Journal, 2013, 7, 45.
  14. Han, D.Q., Zhao, J., Xu, J., Peng, H.S., Chen, X.J., Li, S.P. Quality evaluation of Polygonum multiflorum in China based on HPLC analysis of hydrophilic bioactive compounds and chemometrics. Journal of Pharmaceutical and Biomedical Analysis, 2013, 72, 223-230.
  15. Chen, X.J., Dinh, N.P., Zhao, J., Wang, Y.T., Li, S.P., Svec, F. Effect of ion adsorption on CEC separation of small molecules using hypercrosslinked porous polymer monolithic capillary columns. Journal of Separation Science, 2012, 35(12), 1502-1505.
  16. Chen, X.J., Zhao, J., Wang, Y.T., Huang, L.Q., Li, S.P. CE and CEC analysis of phytochemicals in herbal medicines. Electrophoresis, 2012, 33(1), 168-179.
  17. Xu, J., Guan, J., Chen, X.J., Zhao, J., Li, S.P. Comparison of polysaccharides from different Dendrobium using saccharide mapping. Journal of Pharmaceutical and Biomedical Analysis, 2011, 55(5), 977-983.
  18. Chen, X.J., Yang, F.Q., Wang, Y.T., Li, S.P. CE and CEC of nucleosides and nucleotides in food materials. Electrophoresis, 2010, 31(13), 2092-2105.
  19. Chen, X.J., Zhao, J., Meng, Q., Li, S.P., Wang, Y.T. Simultaneous determination of five flavonoids in licorice using pressurized liquid extraction and capillary electrochromatography coupled with peak suppression diode array detection. Journal of Chromatography A, 2009, 1216(43), 7329-7335.
  20. Jiang, Y., Li, S.P.,Wang, Y.T., Chen, X.J., Tu, P.F. Differentiation of Herba Cistanches by fingerprint with high-performance liquid chromatography-diode array detection-mass spectrometry. Journal of Chromatography A, 2009, 1216(11), 2156-2162.
  21. Chen, X.J., Tu, P.F., Jiang, Y., Wang, Y.T., Li, S.P. Effect of stability of internal standard on quantification of 15 flavonoids in Epimedium using CZE. Journal of Separation Science, 2009, 32(2), 275-281.
  22. Chen, X.J., Ji, H., Wang, Y.T., Li, S.P. Simultaneous determination of seven flavonoids in Epimedium using pressurized liquid extraction and capillary electrochromatography. Journal of Separation Science, 2008, 31(5), 881-887.
  23. Chen, X.J., Ji, H., Zhang, Q.W., Tu, P.F., Wang, Y.T., Guo, B.L., Li, S.P. A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis, 2008, 46(2), 226-235.
  24. Chen, X.J., Guo, B.L., Li, S.P., Zhang, Q.W., Tu, P.F., Wang, Y.T. Simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and high-performance liquid chromatography. Journal of Chromatography A, 2007, 1163(1-2), 96-104.
  25. Jiang, Y., Tu, P.F., Chen, X.J., Zhang, T.Y. Isolation of two sucrose esters from Polygala tenuifolia by high speed countercurrent chromatography. Journal of Liquid Chromatography & Related Technologies, 2005, 28(10), 1583-1592.
  26. Zhang, Y.J., Qian, Z.M., Chen, X.J., Yang, F.Q., Li, S.P. Simultaneous HPLC determination of uridine, adenine, guanosine, and adenosine in six tonic traditional Chinese medicines. Chinese Journal of Pharmaceutical Analysis, 2010, 30(1), 33-36.
  27. Chen, X.J., Li, S.P., Wang, Y.T., Tu, P.F. Comparison of quantitative determination of flavonoids in Herba Epimedii by HPLC, UPLC and CZE. Chinese Pharmaceutical Journal, 2008, 43 (8), 624-628.
  28. Chen, X.J., Zhang, Q.W., Ji, H., Wang, Y.T., Tu, P.F., Li, S.P. Comparison of UV spectrophotometry and HPLC on quantitative determination of total flavonoids of Herba Epimedii. Chinese Journal of Pharmaceutical Analysis, 2007, 27(5), 625-630.

 

 

 

Book and Book Chapters

  1. Li, S.P., Chen, X.J., Yang, F.Q. Application of chemometrics in capillary electrophoresis analysis of herbal medicines. In: Hanrahan, G., Gomez, F.A. (Eds.), Chemometric methods in capillary electrophoresis (pp. 227-242). Hoboken, New Jersey. John Wiley & Sons, Inc., 2010.
  2. Chen, X.J. (associate editor). In: Li, S.P., Wang, Y.T. (Eds.), Chromatographic methods for analysis of commonly used Chinese herbs. Macao. Publications Center, University of Macau. (ISBN: 978-99937-970-6-7), 2009.
  3. Chen, X.J., Wang, Y.T., Li, S.P. Yinyanghuo (Epimedium spp.) In: Li, S.P., Wang, Y.T. (Eds.), Pharmacological Activity-Based Quality Control of Chinese Herbs. (pp. 217-234) New York. Nova Publishers, Inc., 2008.
  4. Guan, J., Chen, X.J., Li, SP. Recent development on analytical techniques for quality control of Chinese herbs. In: Li, S.P., Wang, Y.T. (Eds.), Pharmacological Activity-Based Quality Control of Chinese Herbs. (pp. 73-113) New York. Nova Publishers, Inc., 2008.

 

 

Awards

  1. Chen, X.J. Scientific and Technological R&D Award for Postgraduates, Macao Special Administrative Region. Macao Science and Technology Development Fund, 2012.
  2. Chen, X.J., Dinh, N.P., Zhao, J., Li, S.P., Wang, Y.T., Irgum, K., Svec, F. Effect of ion adsorption on capillary electrochromatographic separation of small molecules using hypercrosslinked monolithic capillary columns. CASSS Student Travel Grants. The 38th International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2012), 2012.
  3. Li, S.P., Wang, Y.T., Yang, F.Q., Li, P., Wan, J.B., Chen, X.J. Application of pressurized liquid extraction in quality control of Chinese medicine. 3rd Prize of the Science and Technology Award, Chinese Pharmaceutical Association, 2008.
  4. Chen, X.J., Li, S.P., Wang, Y.T. Comparison of HPLC, UPLC and CZE on quantitative determination of flavonoids in Herba Epimedii. Excellent Paper 2nd Prize. The 8th "SHIMADZU CUP" of National Pharmaceutical Analysis Symposium, Chinese Pharmaceutical Association, 2007.

 

 

 

Qualifications

 

 

Contact Details

Institute of Chinese Medical Sciences
University of Macau
Avenida da Universidade, Taipa, Macao SAR

Room 6007, N22
Tel: (853) 8822-4915
Fax: (853) 2884-1358


E-mail: xiaojiachen@umac.mo